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Home >Pharmaceutical> Phenoxybenzamine hydrochloride
- Chemical Name:Phenoxybenzamine hydrochloride
- CAS No.:63-92-3
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What is the Phenoxybenzamine hydrochloride ?
Phenoxybenzamine hydrochloride is White crystalline powder., while it's Molecular Formula is C18H22 Cl N O . Cl H. Phenoxybenzamine (5.0 to 60.0 mg/day) is used in order to control episodes of hypertension and sweating, it has a relatively slow onset and prolonged effect when compared to alternative α-blockers. If tachycardia is excessive, it may also be necessary to use a betablocker concomitantly. In addition, phenoxybenzamine has been tested for its efficacy in micturition disorders resulting from neurogenic bladder, functional outlet obstruction, and partial prostatic obstruction.
What is the CAS number for Phenoxybenzamine hydrochloride ?
The CAS number of Phenoxybenzamine hydrochloride is 63-92-3.
More information of Phenoxybenzamine hydrochloride 63-92-3 are:
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Synonyms |
Benzenemethanamine,N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride (9CI);Benzylamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride(7CI,8CI); 2-(N-Benzyl-2-chloroethylamino)-1-phenoxypropane hydrochloride;Dibenzylin; Dibenzyline chloride; Dibenzyline hydrochloride; Dibenzyran; N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine,hydrochloride; N-2-Phenoxyisopropyl-N-benzyl-b-chloroethylamine hydrochloride; NSC 37448;Phenoxybenzamine chloride; Phenoxybenzamine hydrochloride |
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CAS?Number |
63-92-3 |
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Molecular Formula |
C18H22 Cl N O . Cl H |
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Molecular Weight |
340.293 |
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Melting Point |
137.5 ºC |
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Boiling Point |
381.5 °C at 760 mmHg |
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Flash Point |
184.5 °C |
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HS CODE |
2922299090 |
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PSA |
12.47000 |
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LogP |
4.99690 |
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Pka |
pKa 4.4 (Uncertain) |
What is Phenoxybenzamine hydrochloride (63-92-3) used for?
Phenoxybenzamine hydrochloride (dibenzyline) is an orally effective, long-acting non-selective (alpha1 and alpha2) alpha-adrenoceptor blocking agent. It is used for the control of episodes of hypertension associated withpheochromocytoma. It literally produces a "chemical sympathectomy". It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. The initialdose is 10 mg/day, increased by 10 mg every 4 days till the desired response is attained.The usual dosage range is 20-60mg/day.
InChI:InChI=1/C18H22ClNO/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17/h2-11,16H,12-15H2,1H3/p+1
Articles related to Phenoxybenzamine hydrochloride:
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Article |
Source |
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A PROCESS FOR THE PREPARATION OF PHENOXYBENZAMINE |
- Page/Page column 10; 12, (2018/08/03) |
How to get the best price on Phenoxybenzamine hydrochloride?
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