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- Chemical Name: Brompheniramine
- CAS No.: 86-22-6
Chinese Manufacturer supply Brompheniramine 86-22-6 in stock with high standard
- Molecular Formula: C16H19BrN2
- Molecular Weight: 319.244
- Appearance/Colour: Oily liquid with slightly yellow color. Characteristic amine-like.
- Vapor Pressure: 1.05E-06mmHg at 25°C
- Melting Point: 25°C
- Refractive Index: 1.5770 (estimate)
- Boiling Point: 403 °C at 760 mmHg
- PKA: pKa 3.59 (Uncertain)
- Flash Point: 197.5 °C
- PSA： 16.13000
- Density: 1.265 g/cm3
- LogP: 3.92770
Brompheniramine(Cas 86-22-6) Usage
|
Definition |
ChEBI: Pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic cond tions, including rhinitis and conjunctivitis. |
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Brand name |
Dimetane (Wyeth). |
InChI:InChI=1/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3
86-22-6 Relevant articles
New Synthetic Route to Pheniramines via Hydroformylation of Functionalized Olefins
Botteghi, Carlo,Chelucci, Giorgio,Ponte, Gino Del,Marchetti, Mauro,Paganelli, Stefano
, p. 7125 - 7127 (2007/10/02)
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THE REDUCTIVE DECYANATION OF NITRILES BY ALKALI FUSION
Berkoff, Charles E.,Rivard, Donald E.,Kirkpatrick, David,Ives, Jeffrey L.
, p. 939 - 946 (2007/10/02)
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86-22-6 Process route
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172274-26-9
2-(4-Bromo-phenyl)-4-dimethylamino-butyronitrile
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74-86-2,25067-58-7
acetylene
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86-22-6,132-21-8,32188-07-1,32656-44-3
brompheniramine
| Conditions | Yield |
|---|---|
|
(η5-cyclopentadienyl)-η4-cycloocta-1,5-dienecobalt(I);
In
toluene;
at 140 ℃;
for 36h;
under 10640 Torr;
|
70%
|
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65676-22-4
2-(4-Bromo-phenyl)-4-dimethylamino-2-pyridin-2-yl-butyronitrile
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86-22-6,132-21-8,32188-07-1,32656-44-3
brompheniramine
| Conditions | Yield |
|---|---|
|
With
potassium hydroxide;
at 150 ℃;
for 4h;
|
75%
|
86-22-6 Upstream products
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74129-15-0
2-(4-bromobenzyl)pyridine
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107-99-3
2-(dimethylamino)ethyl chloride
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65676-22-4
2-(4-Bromo-phenyl)-4-dimethylamino-2-pyridin-2-yl-butyronitrile
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172274-26-9
2-(4-Bromo-phenyl)-4-dimethylamino-butyronitrile