.png)
- Chemical Name: 4-METHYL-1-PHENYL-2-PENTANOL
- CAS No.: 7779-78-4
Manufacturer Sells Best Quality 4-METHYL-1-PHENYL-2-PENTANOL 7779-78-4 with stock
- Molecular Formula: C12H18O
- Molecular Weight: 178.274
- Appearance/Colour: colourless slightly oily liquid with a green-floral, fresh, slightly sweet odour
- Vapor Pressure: 0.224mmHg at 25°C
- Refractive Index: 1.509
- Boiling Point: 198.3 °C at 760 mmHg
- Flash Point: 79.4 °C
- PSA： 20.23000
- Density: 0.955 g/cm3
- LogP: 2.63610
4-METHYL-1-PHENYL-2-PENTANOL(Cas 7779-78-4) Usage
|
Preparation |
By reacting isobutyl aldehyde with benzyl magnesium chloride. |
|
Biochem/physiol Actions |
Taste at 10 ppm |
|
Synthesis |
4-Methyl-1-phenyl-2-pentanol is prepared from benzyl chloride to benzyl magnesium bromide, and then hydrolyzed with isovaleraldehyde after Grignard reaction. |
|
Aroma threshold values |
Aroma characteristics at 1.0%: herbaceous, warm celery-like, musk and creamy with a slight floral citrus nuance |
|
Taste threshold values |
Taste characteristics at 10 ppm: warm, amber sclarolide herbaceous celery-like with oily and creamy nuances. |
InChI:InChI=1/C12H18O/c1-10(2)8-12(13)9-11-6-4-3-5-7-11/h3-7,10,12-13H,8-9H2,1-2H3
7779-78-4 Relevant articles
C-H Alkylation of Aldehydes by Merging TBADT Hydrogen Atom Transfer with Nickel Catalysis
Murugesan, Vetrivelan,Ganguly, Anirban,Karthika, Ardra,Rasappan, Ramesh
supporting information, p. 5389 - 5393 (2021/07/21)
Catalyst controlled site-selective C-H f...
A General Regioselective Synthesis of Alcohols by Cobalt-Catalyzed Hydrogenation of Epoxides
Beller, Matthias,Junge, Kathrin,Leischner, Thomas,Li, Wu,Liu, Weiping
supporting information, p. 11321 - 11324 (2020/05/16)
A straightforward methodology for the sy...
Photocatalytic carbanion generation-benzylation of aliphatic aldehydes to secondary alcohols
Donabauer, Karsten,Maity, Mitasree,Berger, Anna Lucia,Huff, Gregory S.,Crespi, Stefano,K?nig, Burkhard
, p. 5162 - 5166 (2019/06/05)
We present a redox-neutral method for th...
Screening on the use of Kluyveromyces marxianus CBS 6556 growing cells as enantioselective biocatalysts for ketone reductions
Vitale, Paola,Perna, Filippo Maria,Perrone, Maria Grazia,Scilimati, Antonio
body text, p. 1985 - 1993 (2012/03/22)
The versatility of Kluyveromyces marxian...
7779-78-4 Process route
-
-
65473-82-7
2-isobutyl-3-phenyloxirane
-
-
7779-78-4
(±)-4-methyl-1-phenyl-2-pentanol
| Conditions | Yield |
|---|---|
|
With
cobalt(II) bis[bis((trifluoromethyl)sulfonyl)amide]; hydrogen; zinc trifluoromethanesulfonate; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine];
In
tetrahydrofuran;
at 80 ℃;
for 16h;
under 30003 Torr;
regioselective reaction;
Autoclave;
|
85%
|
-
-
770-09-2
benzyltrimethylsilane
-
-
590-86-3
isovaleraldehyde
-
-
7779-78-4
(±)-4-methyl-1-phenyl-2-pentanol
| Conditions | Yield |
|---|---|
|
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
for 3h;
room temp. then reflux;
|
68%
|
|
With
silica gel;
tetrabutyl ammonium fluoride;
Yield given. Multistep reaction;
1.) THF, 30 min, room t. then reflux, 12 h; 2.) methylene dichloride;
|
7779-78-4 Upstream products
-
122-78-1
phenylacetaldehyde
-
100-44-7
benzyl chloride
-
590-86-3
isovaleraldehyde
-
770-09-2
benzyltrimethylsilane